Pruning tiny budsites in WEEK 5 of FLOWERING?

It could stress her and make her go hermie, but even then look at the bright side. Feminized seeds for free if she goes hermie from female since those seeds will be feminized, and you can take the seeds out and do some dry sift with the flower to not risk getting more seeds, you can then use the leftover from that to make some really good cannabutter to have edibles for ages. If you have another strain nearby and she goes hermie, i would go as far as rubbing her all over my other female, some trans on fem action and shit would yield a pretty femined unknown cross wich could be a bad one, a cool one, or something completely new where you can reach even 40% thc, we just never know with new crosses. Overall, its possible but not the most probable outcome for her to hermie, so i would do it.